At Northern Voice, Darren Barefoot is asking why there is so little profound art on the web, but I think there is so much profound art that I cannot keep up with it. Perhaps it is because we have different filters for what is profound, but here are some sites that I frequently find art that speaks to me.
Dresden Codec: Dungeons and Discourse
NASA Astronomy Picture of the Day
Structure Synth http://flickr.com/groups/structuresynth/
GapMinder (profound statistics)
Film is not dead, it just smells funny
We Make Money Not Art
While I cannot keep up with all the art that I come across, I can find a social connection between all of these. The best, most moving art doesn't just inspire me to admire it or think about it, but to share it with my friends and to create art that I wouldn't have created otherwise.